Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion
نویسندگان
چکیده
منابع مشابه
Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats.
BACKGROUND AND PURPOSE Thrombolytic therapy with tissue plasminogen activator (tPA) for acute ischemic stroke remains complicated by risks of hemorrhagic transformation. In this study we used a previously established quantitative rat model of tPA-associated hemorrhage to test the hypothesis that matrix metalloproteinases (MMPs) are involved. METHODS Spontaneously hypertensive rats were subjec...
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15 صفحه اولMinocycline protects against delayed cerebral ischemia after subarachnoid hemorrhage via matrix metalloproteinase‐9 inhibition
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ژورنال
عنوان ژورنال: Neuroscience
سال: 2013
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2013.08.068